Response to Protocol Review Scenario: Inappropriate IO Action

Computerised decision to reduce inappropriate medication in the elderly: a systematic review with meta-analysis protocol

INTRODUCTION Life expectancy continues to increase in developed countries. Elderly people are more likely to consume more medications and become vulnerable to age-related changes in drugs' pharmacokinetics and pharmacodynamics. Recent studies have identified opportunities and barriers for deprescribing potentially inappropriate medications. It has already been demonstrated that computerised dec...

Neuregulins Response to Exercise: a Mini Review

The Neuregulin is a member of the epidermal growth factors (EGF) family of receptor kinases, was originally identified as the product of the transforming gene derived from chemically induced rat neuroblastoms. A variety of different protein isoforms are produced from single Neuregulin gene. Four distinct vertebrate gene encode Neuregulin, prosaically named NRG1, NRG2, NRG3, and NRG4. Most of bi...

Author's response to reviews Title: Inappropriate Medication Use among the Elderly: a Systematic Review Authors:

Fast Pad Redistribution from Periphery-IO to Area-IO

The problem of redistributing IO from bondpads on the periphery of an IC to an array of solder bumps occurs frequently in MCM layout. We show that the commonly held belief that providing enough escapes at the perimeter of the array is not suucient to guarantee routability of the design. We analyze the Even Wiring Distribution (EWD) routing heuristic and show that it produces designs whose criti...

A Scenario-Based Approach to Protocol Design Using Evolutionary Techniques

An evolutionary approach to design communication protocols from scenario-based specifications is presented. It enables to automatically generate finite-state models of protocol entities from Message Sequence Charts. By converting the Message Sequence Charts into input/output sequences, the problem reduces to evolving finite-state machines with the specified input/output behaviors. The proposed ...